[18] Northern Iowa 9-30 Iowa State [24] 2023-09-02 18:00
Stadium: Jack Trice Stadium Round: 1
Home Manager: Matt Campbell Away Manager: Mark Farley
Head to Head
| NCAAF | 2021/09/04 20:30 | Northern Iowa v Iowa State | L | 10-16 |
| NCAAF | 2019/08/31 16:00 | Northern Iowa v Iowa State | L | 26-29 |
| NCAAF | 2017/09/03 00:00 | Northern Iowa v Iowa State | L | 24-42 |
| NCAAF | 2016/09/04 00:00 | Iowa State v Northern Iowa | W | 20-25 |
| NCAAF | 2015/09/06 00:00 | Iowa State v Northern Iowa | L | 31-7 |
| NCAAF | 2011/09/03 12:00 | Iowa State v Northern Iowa | L | 20-19 |
| NCAAF | 2010/09/25 12:00 | Iowa State v Northern Iowa | L | 27-0 |
| NCAAF | 2007/09/08 12:00 | Iowa State v Northern Iowa | W | 13-24 |
Home History
| NCAAF | 2022/11/19 19:00 | Northern Iowa v South Dakota | W | 58-14 |
| NCAAF | 2022/11/05 21:00 | South Dakota State v Northern Iowa | L | 31-28 |
| NCAAF | 2022/10/29 19:00 | Northern Iowa v SO Illinois | W | 37-36 |
| NCAAF | 2022/10/22 21:00 | Missouri St v Northern Iowa | W | 20-41 |
| NCAAF | 2022/10/15 21:00 | Utah Tech v Northern Iowa | W | 14-41 |
| NCAAF | 2022/10/08 21:00 | Illinois State v Northern Iowa | L | 23-21 |
| NCAAF | 2022/10/01 21:00 | Indiana State v Northern Iowa | W | 14-20 |
| NCAAF | 2022/09/24 20:00 | Northern Iowa v Western Illinois | W | 52-17 |
Away History
| NCAAF | 2022/11/26 21:00 | Iowa State v TCU | L | 14-62 |
| NCAAF | 2022/11/20 00:00 | Texas Tech v Iowa State | L | 14-10 |
| NCAAF | 2022/11/12 20:30 | Iowa State v Oklahoma State | L | 14-20 |
| NCAAF | 2022/11/05 19:30 | West Virginia v Iowa State | W | 14-31 |
| NCAAF | 2022/10/29 16:00 | Oklahoma v Iowa State | L | 27-13 |
| NCAAF | 2022/10/15 16:00 | Iowa State v Texas | L | 21-24 |
| NCAAF | 2022/10/08 23:30 | Kansas State v Iowa State | L | 10-9 |
| NCAAF | 2022/10/01 19:30 | Iowa State v Kansas | L | 11-14 |