Stadium: Daytona Stadium Round: 1
Home Manager: Raymond Woodie Away Manager: Kendrick Wade
| NCAAF | 2022/10/22 20:00 | Bethune Cookman v Mississippi Valley State | L | 45-35 |
| NCAAF | 2021/10/09 20:00 | Mississippi Valley State v Bethune Cookman | W | 20-14 |
| NCAAF | 2019/09/21 23:00 | Bethune Cookman v Mississippi Valley State | L | 22-6 |
| NCAAF | 2018/10/06 20:00 | Mississippi Valley State v Bethune Cookman | L | 27-41 |
| NCAAF | 2023/10/28 19:00 | Mississippi Valley State v Alcorn State | L | 3-24 |
| NCAAF | 2023/10/21 19:00 | Jackson State v Mississippi Valley State | L | 21-6 |
| NCAAF | 2023/10/14 19:00 | Arkansas Pine Bluff v Mississippi Valley State | W | 17-42 |
| NCAAF | 2023/10/07 23:00 | Mississippi Valley State v Prairie View | L | 12-31 |
| NCAAF | 2023/09/30 23:00 | Florida A&M v Mississippi Valley State | L | 31-7 |
| NCAAF | 2023/09/23 19:00 | Mississippi Valley State v North Carolina Central | L | 3-45 |
| NCAAF | 2023/09/16 23:00 | Delta State v Mississippi Valley State | L | 35-7 |
| NCAAF | 2023/09/02 20:00 | Mississippi Valley State v Central State | L | 21-24 |
| NCAAF | 2023/10/28 19:00 | Bethune Cookman v Grambling State | L | 14-28 |
| NCAAF | 2023/10/21 20:00 | Southern v Bethune Cookman | L | 28-18 |
| NCAAF | 2023/10/14 19:00 | Texas Southern Tigers v Bethune Cookman | L | 34-31 |
| NCAAF | 2023/10/07 19:00 | Bethune Cookman v Alabama State | L | 14-19 |
| NCAAF | 2023/09/23 23:00 | Bethune Cookman v Jackson State | L | 16-22 |
| NCAAF | 2023/09/14 23:30 | Bethune Cookman v Miami Florida | L | 7-48 |
| NCAAF | 2023/09/09 20:00 | Bethune Cookman v Savannah State | W | 31-6 |
| NCAAF | 2023/09/02 23:00 | Bethune Cookman v Memphis | L | 14-56 |