Stadium: Dana J. Dykhouse Stadium Round: 1
Home Manager: Jimmy Rogers Away Manager: Ryan Beard
| NCAAF | 2022/09/24 19:00 | South Dakota State v Missouri St | L | 28-14 |
| NCAAF | 2019/11/02 19:00 | South Dakota State v Missouri St | L | 35-14 |
| NCAAF FCS | 2018/11/03 19:00 | Missouri St v South Dakota State | L | 7-59 |
| NCAAF | 2017/10/21 19:00 | Missouri St v South Dakota State | L | 30-62 |
| NCAAF | 2023/11/11 20:00 | Northern Iowa v Missouri St | W | 16-35 |
| NCAAF | 2023/11/04 19:00 | Illinois State v Missouri St | L | 36-35 |
| NCAAF | 2023/10/28 18:00 | Missouri St v Youngstown State | L | 28-44 |
| NCAAF | 2023/10/21 19:00 | Murray State v Missouri St | W | 24-28 |
| NCAAF | 2023/10/14 20:00 | Missouri St v Western Illinois | W | 48-7 |
| NCAAF | 2023/10/07 19:00 | North Dakota State v Missouri St | L | 38-10 |
| NCAAF | 2023/09/30 21:00 | Missouri St v SO Illinois | L | 20-33 |
| NCAAF | 2023/09/23 19:00 | Utah Tech v Missouri St | W | 14-59 |
| NCAAF | 2023/11/11 17:00 | South Dakota State v Youngstown State | W | 34-0 |
| NCAAF | 2023/11/04 19:00 | North Dakota State v South Dakota State | W | 16-33 |
| NCAAF | 2023/10/28 18:00 | South Dakota State v South Dakota | W | 37-3 |
| NCAAF | 2023/10/21 19:00 | South Dakota State v SO Illinois | W | 17-10 |
| NCAAF | 2023/10/14 19:00 | Northern Iowa v South Dakota State | W | 6-41 |
| NCAAF | 2023/10/07 23:00 | South Dakota State v Illinois State | W | 40-21 |
| NCAAF | 2023/09/30 19:00 | North Dakota v South Dakota State | W | 21-42 |
| NCAAF | 2023/09/16 19:30 | Drake Bulldogs v South Dakota State | W | 7-70 |