Stadium: Fred G. Hughes Stadium Round: 1
| NCAAF | 2022/09/25 00:00 | Fort Hays State University Tigers v Missouri Southern Lions | W | 24-25 |
| NCAAF | 2021/09/25 19:00 | Missouri Southern Lions v Fort Hays State University Tigers | L | 21-42 |
| NCAAF | 2019/09/29 00:00 | Fort Hays State University Tigers v Missouri Southern Lions | L | 44-3 |
| NCAAF | 2018/09/22 23:00 | Missouri Southern Lions v Fort Hays State University Tigers | L | 20-55 |
| NCAAF | 2023/09/30 19:00 | Central Oklahoma v Missouri Southern Lions | L | 30-27 |
| NCAAF | 2023/09/23 19:00 | Missouri Southern Lions v Northeastern State Riverhawks | W | 42-0 |
| NCAAF | 2023/09/16 17:00 | Nebraska Kearney v Missouri Southern Lions | W | 13-18 |
| NCAAF | 2023/09/07 23:00 | Washburn Ichabods Football v Missouri Southern Lions | W | 23-30 |
| NCAAF | 2023/09/01 00:00 | Missouri Southern Lions v NW Missouri State | L | 24-31 |
| NCAAF | 2022/11/12 20:00 | Missouri Southern Lions v Washburn Ichabods Football | L | 20-37 |
| NCAAF | 2022/11/05 18:30 | NW Missouri State v Missouri Southern Lions | L | 27-5 |
| NCAAF | 2022/10/29 18:00 | Missouri Western Griffons v Missouri Southern Lions | L | 31-27 |
| NCAAF | 2023/10/01 00:00 | Fort Hays State University Tigers v Blue Tigers | W | 71-3 |
| NCAAF | 2023/09/23 18:00 | Missouri Western Griffons v Fort Hays State University Tigers | L | 28-7 |
| NCAAF | 2023/09/17 00:00 | Fort Hays State University Tigers v NW Missouri State | W | 17-6 |
| NCAAF | 2023/09/08 00:00 | Fort Hays State University Tigers v Pittsburgh State Gorillas | L | 14-40 |
| NCAAF | 2023/08/31 23:00 | Northeastern State Riverhawks v Fort Hays State University Tigers | W | 0-56 |
| NCAAF | 2022/11/12 20:00 | Pittsburgh State Gorillas v Fort Hays State University Tigers | L | 35-14 |
| NCAAF | 2022/11/05 18:00 | Fort Hays State University Tigers v Northeastern State Riverhawks | W | 27-14 |
| NCAAF | 2022/10/29 19:00 | Emporia State v Fort Hays State University Tigers | L | 42-14 |