Stadium: Fred G. Hughes Stadium Round: 1
| NCAAF | 2022/09/25 00:00 | Fort Hays State University Tigers v Missouri Southern Lions | W | 24-25 |
| NCAAF | 2021/09/25 19:00 | Missouri Southern Lions v Fort Hays State University Tigers | L | 21-42 |
| NCAAF | 2019/09/29 00:00 | Fort Hays State University Tigers v Missouri Southern Lions | L | 44-3 |
| NCAAF | 2018/09/22 23:00 | Missouri Southern Lions v Fort Hays State University Tigers | L | 20-55 |