Head to Head
| NFL | 2017/12/10 18:00 | IND Colts v BUF Bills | W | 7-13 |
| NFL Preseason | 2016/08/13 23:00 | BUF Bills v IND Colts | L | 18-19 |
| NFL | 2015/09/13 17:00 | BUF Bills v IND Colts | W | 27-14 |
Home History
| NFL | 2018/10/14 17:00 | BUF Bills v HOU Texans | L | 13-20 |
| NFL | 2018/10/07 17:00 | TEN Titans v BUF Bills | W | 12-13 |
| NFL | 2018/09/30 17:00 | BUF Bills v GB Packers | L | 0-22 |
| NFL | 2018/09/23 17:00 | BUF Bills v MIN Vikings | W | 27-6 |
| NFL | 2018/09/16 17:00 | LA Chargers v BUF Bills | L | 31-20 |
| NFL | 2018/09/09 17:00 | BUF Bills v BAL Ravens | L | 3-47 |
| NFL Preseason | 2018/08/31 00:00 | BUF Bills v CHI Bears | W | 28-27 |
| NFL Preseason | 2018/08/26 20:00 | CIN Bengals v BUF Bills | L | 26-13 |
Away History
| NFL | 2018/10/14 17:00 | IND Colts v NY Jets | L | 34-42 |
| NFL | 2018/10/05 00:20 | IND Colts v NE Patriots | L | 24-38 |
| NFL | 2018/09/30 17:00 | HOU Texans v IND Colts | L | 37-34 |
| NFL | 2018/09/23 17:00 | IND Colts v PHI Eagles | L | 16-20 |
| NFL | 2018/09/16 17:00 | IND Colts v WAS Commanders | W | 21-9 |
| NFL | 2018/09/09 17:00 | CIN Bengals v IND Colts | L | 34-23 |
| NFL Preseason | 2018/08/30 23:00 | IND Colts v CIN Bengals | W | 27-26 |
| NFL Preseason | 2018/08/25 20:30 | SF 49ers v IND Colts | W | 17-23 |