[4] Santos Laguna 2-0 Tigres [5] 2018-05-06 23:00
Weather: Good Stadium: Estadio TSM Corona Pitch: Good Round: 3
Referee: Jorge Isaac Rojas Castillo Home Manager: Robert Siboldi Away Manager: Ricardo Ferretti
Head to Head
| Mexico Liga MX | 2018/05/04 00:30 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2018/01/14 01:00 | Tigres UANL v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2017/07/30 23:30 | Santos Laguna v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2017/01/08 01:00 | Tigres UANL v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2016/07/17 23:00 | Santos Laguna v Tigres UANL | D | 0-0 |
| Mexico Liga MX | 2016/04/24 00:00 | Santos Laguna v Tigres UANL | W | 2-1 |
| Mexico Liga MX | 2015/11/01 01:00 | Tigres UANL v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2015/05/17 00:00 | Tigres UANL v Santos Laguna | W | 0-1 |
Home History
| Mexico Liga MX | 2018/05/04 00:30 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2018/04/29 02:00 | Club America v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2018/04/22 23:00 | Santos Laguna v Unam Pumas | L | 1-2 |
| Mexico Liga MX | 2018/04/15 00:06 | Pachuca v Santos Laguna | L | 3-1 |
| Mexico Liga MX | 2018/04/08 23:00 | Santos Laguna v Queretaro | W | 3-0 |
| Mexico Cup | 2018/04/05 02:15 | Necaxa v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2018/03/31 03:00 | Atlas v Santos Laguna | L | 3-2 |
| Mexico Liga MX | 2018/03/17 01:00 | Puebla v Santos Laguna | W | 0-1 |
Away History
| Mexico Liga MX | 2018/05/04 00:30 | Tigres UANL v Santos Laguna | W | 2-0 |
| Mexico Liga MX | 2018/04/29 00:00 | Tigres UANL v Monterrey | D | 2-2 |
| Mexico Liga MX | 2018/04/22 02:00 | Necaxa v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2018/04/15 00:00 | Tigres UANL v Cruz Azul | D | 2-2 |
| Mexico Liga MX | 2018/04/08 17:00 | Toluca v Tigres UANL | L | 1-0 |
| Mexico Liga MX | 2018/04/01 01:00 | Tigres UANL v Leon | W | 4-1 |
| World Club Friendlies | 2018/03/24 23:00 | Tigres UANL v Chivas Guadalajara | W | 2-0 |
| Mexico Liga MX | 2018/03/18 03:06 | Chivas Guadalajara v Tigres UANL | D | 0-0 |