Head to Head
| Mexico Liga MX | 2024/01/27 23:00 | Leon v Santos Laguna | W | 3-2 |
| Mexico Liga MX | 2023/11/27 02:06 | Leon v Santos Laguna | W | 3-2 |
| Mexico Liga MX | 2023/10/09 01:05 | Santos Laguna v Leon | W | 0-2 |
| Mexico Liga MX | 2023/03/20 03:05 | Leon v Santos Laguna | W | 4-1 |
| Mexico Liga MX | 2022/08/19 00:00 | Santos Laguna v Leon | L | 2-1 |
| Mexico Liga MX | 2022/04/25 00:00 | Santos Laguna v Leon | D | 1-1 |
| Mexico Liga MX | 2021/08/22 00:00 | Leon v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2021/03/22 01:06 | Santos Laguna v Leon | W | 1-2 |
Home History
| America Friendlies | 2024/06/27 02:00 | Leon v Irapuato | W | 3-0 |
| Mexico Liga MX | 2024/04/27 23:06 | Juarez FC v Leon | D | 1-1 |
| Mexico Liga MX | 2024/04/20 23:00 | Leon v Monterrey | W | 2-0 |
| Mexico Liga MX | 2024/04/15 00:00 | Unam Pumas v Leon | L | 1-0 |
| Mexico Liga MX | 2024/04/06 23:00 | Leon v Queretaro | L | 0-2 |
| Mexico Liga MX | 2024/04/01 01:00 | Necaxa v Leon | W | 1-2 |
| Mexico Liga MX | 2024/03/17 01:00 | Leon v Puebla | W | 2-1 |
| Mexico Liga MX | 2024/03/09 23:05 | Chivas Guadalajara v Leon | W | 1-2 |
Away History
| Mexico Liga MX | 2024/04/29 00:00 | Santos Laguna v Atletico San Luis | L | 0-3 |
| Mexico Liga MX | 2024/04/21 01:05 | Santos Laguna v Pachuca | L | 0-2 |
| Mexico Liga MX | 2024/04/13 03:00 | Necaxa v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2024/04/07 03:05 | Santos Laguna v Club America | D | 1-1 |
| Mexico Liga MX | 2024/04/01 01:36 | Juarez FC v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2024/03/16 03:00 | Tijuana v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2024/03/10 01:00 | Santos Laguna v Cruz Azul | W | 3-0 |
| Mexico Liga MX | 2024/03/02 01:00 | Queretaro v Santos Laguna | W | 0-1 |