[39] Southern Illinois 13-42 South Dakota [25] 2024-09-28 18:00
Stadium: DakotaDome Round: 1
Home Manager: Bob Nielson Away Manager: Nick Hill
Head to Head
| NCAAF | 2023/11/04 18:00 | South Dakota v SO Illinois | L | 14-7 |
| NCAAF | 2022/10/22 19:00 | SO Illinois v South Dakota | L | 24-27 |
| NCAAF | 2021/11/27 23:00 | SO Illinois v South Dakota | W | 22-10 |
| NCAAF | 2019/10/26 21:00 | SO Illinois v South Dakota | W | 48-28 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | L | 31-24 |
| NCAAF | 2017/10/28 20:00 | South Dakota v SO Illinois | L | 42-0 |
Home History
| NCAAF | 2024/09/21 23:00 | SE Missouri St v SO Illinois | L | 38-21 |
| NCAAF | 2024/09/14 23:00 | Incarnate Word v SO Illinois | W | 28-35 |
| NCAAF | 2024/09/07 23:00 | SO Illinois v Austin Peay | W | 31-17 |
| NCAAF | 2024/09/01 00:00 | SO Illinois v BYU | L | 13-41 |
| NCAAF | 2023/12/03 03:00 | SO Illinois v Idaho | L | 17-20 |
| NCAAF | 2023/11/25 20:00 | Nicholls State v SO Illinois | W | 0-35 |
| NCAAF | 2023/11/18 19:00 | Indiana State v SO Illinois | W | 9-38 |
| NCAAF | 2023/11/11 20:30 | SO Illinois v North Dakota State | L | 10-34 |
Away History
| NCAAF | 2024/09/21 18:00 | Drake Bulldogs v South Dakota | W | 3-42 |
| NCAAF | 2024/09/07 19:30 | South Dakota v Wisconsin | L | 13-27 |
| NCAAF | 2024/08/30 00:00 | South Dakota v Northern State Wolves | W | 45-3 |
| NCAAF | 2023/12/09 19:30 | North Dakota State v South Dakota | L | 45-17 |
| NCAAF | 2023/12/02 19:00 | CS Sacramento v South Dakota | W | 24-34 |
| NCAAF | 2023/11/18 19:00 | South Dakota v Western Illinois | W | 48-6 |
| NCAAF | 2023/11/11 18:00 | North Dakota v South Dakota | W | 10-14 |
| NCAAF | 2023/11/04 18:00 | South Dakota v SO Illinois | W | 14-7 |