Central Michigan 20-31 Michigan State 2018-09-29 16:00
Stadium: Spartan Stadium Round: 1
Home Manager: Mark Dantonio Away Manager: John Bonamego
Head to Head
| NCAAF | 2015/09/26 16:00 | Michigan State v Central Michigan | L | 30-10 |
| NCAAF | 2012/09/08 12:00 | Central Michigan v Michigan State | L | 7-41 |
| NCAAF | 2011/09/24 12:00 | Michigan State v Central Michigan | L | 45-7 |
| NCAAF | 2009/09/12 12:00 | Michigan State v Central Michigan | W | 27-29 |
| NCAAF | 2004/09/11 12:00 | Michigan State v Central Michigan | L | 24-7 |
| NCAAF | 2001/09/08 12:00 | Michigan State v Central Michigan | L | 35-21 |
Home History
| NCAAF | 2018/09/22 19:00 | Maine v Central Michigan | W | 5-17 |
| NCAAF | 2018/09/15 19:30 | Central Michigan v Northern Illinois | L | 16-24 |
| NCAAF | 2018/09/08 19:00 | Kansas v Central Michigan | L | 31-7 |
| NCAAF | 2018/09/01 19:30 | Central Michigan v Kentucky | L | 20-35 |
| NCAAF | 2017/12/22 21:00 | Central Michigan v Wyoming | L | 14-37 |
| NCAAF | 2017/11/24 17:00 | Northern Illinois v Central Michigan | W | 24-31 |
| NCAAF | 2017/11/15 00:00 | Kent State v Central Michigan | W | 23-42 |
| NCAAF | 2017/11/09 01:00 | Eastern Michigan v Central Michigan | W | 30-42 |
Away History
| NCAAF | 2018/09/22 23:30 | Michigan State v Indiana | W | 35-21 |
| NCAAF | 2018/09/09 02:45 | Michigan State v Arizona State | L | 13-16 |
| NCAAF | 2018/08/31 23:00 | Utah State v Michigan State | W | 31-38 |
| NCAAF | 2017/12/29 02:00 | Michigan State v Washington State | W | 42-17 |
| NCAAF | 2017/11/25 21:00 | Michigan State v Rutgers | W | 40-7 |
| NCAAF | 2017/11/18 21:00 | Maryland v Michigan State | W | 7-17 |
| NCAAF | 2017/11/11 17:00 | Michigan State v Ohio State | L | 3-48 |
| NCAAF | 2017/11/04 16:00 | Penn State v Michigan State | W | 24-27 |