Southern Illinois 3-51 Illinois St 2018-10-13 19:00
Stadium: Hancock Stadium Round: 1
Home Manager: Brock Spack Away Manager: Nick Hill
Home History
| NCAAF | 2018/10/06 22:00 | SO Illinois v Youngstown State | L | 14-17 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | L | 31-24 |
| NCAAF | 2018/09/15 23:00 | SE Missouri St v SO Illinois | L | 48-44 |
| NCAAF | 2018/09/08 20:00 | SO Illinois v Mississippi | L | 41-76 |
| NCAAF | 2018/08/30 23:00 | SO Illinois v Murray State | W | 49-10 |
| NCAAF | 2017/11/18 19:00 | Western Illinois v SO Illinois | L | 28-14 |
| NCAAF | 2017/11/11 19:00 | SO Illinois v Youngstown State | L | 20-28 |
| NCAAF | 2017/11/04 18:00 | SO Illinois v Missouri St | L | 28-36 |
Away History
| NCAAF | 2018/10/06 19:00 | Western Illinois v Illinois State | W | 16-33 |
| NCAAF | 2018/09/29 19:00 | Illinois State v Missouri St | L | 21-24 |
| NCAAF | 2018/09/22 19:00 | Illinois State v Colorado State | W | 35-19 |
| NCAAF | 2018/09/08 23:30 | Eastern Illinois v Illinois State | W | 10-48 |
| NCAAF | 2018/09/01 23:30 | Illinois State v Saint Xavier Cougars | W | 46-0 |
| NCAAF | 2017/11/18 18:00 | Illinois State v North Dakota State | L | 7-20 |
| NCAAF | 2017/11/11 20:00 | South Dakota State v Illinois State | L | 27-24 |
| NCAAF | 2017/11/04 17:00 | Illinois State v Western Illinois | L | 14-31 |