Head to Head
| NFL Preseason | 2019/08/08 23:00 | IND Colts v BUF Bills | L | 16-24 |
| NFL | 2018/10/21 17:00 | BUF Bills v IND Colts | W | 5-37 |
| NFL | 2017/12/10 18:00 | IND Colts v BUF Bills | L | 7-13 |
| NFL Preseason | 2016/08/13 23:00 | BUF Bills v IND Colts | W | 18-19 |
| NFL | 2015/09/13 17:00 | BUF Bills v IND Colts | L | 27-14 |