[17] Elise Mertens 3-6,3-6 Naomi Osaka [2] 2021-03-29 19:00
Stadium: Grandstand Round: 26 Ground: Hardcourt outdoor
Head to Head
| WTA New York | 2020/08/28 15:00 | Elise Mertens v Naomi Osaka | 2-6,6-7 |
| WTA Osaka | 2019/09/21 06:45 | Naomi Osaka v Elise Mertens | 6-4,6-1 |
| WTA Wuhan | 2017/09/25 06:00 | Elise Mertens v Naomi Osaka | 6-4,1-6,6-4 |