[8] La Serena 0-0 Union Espanola [16] 2021-04-24 19:30
Stadium: La Portada Round: 5
Referee: Hector Jona Home Manager: Miguel Ponce Away Manager: Jorge Alberto Pellicer Barcelo
Head to Head
| Chile Primera Division | 2021/02/10 21:30 | Union Espanola v La Serena | D | 1-1 |
| Chile Primera Division | 2020/10/03 14:00 | La Serena v Union Espanola | L | 0-2 |
| World Club Friendlies | 2017/01/17 23:30 | La Serena v Union Espanola | L | 1-2 |