[4] Sevilla 1-0 Villarreal [12] 2021-12-04 13:00
Stadium: Ramon Sanchez Pizjuan Round: 16
Referee: Carlos Del Cerro Grande Home Manager: Julen Lopetegui Away Manager: Unai Emery
Head to Head
| Spain La Liga | 2021/05/16 16:30 | Villarreal v Sevilla | L | 4-0 |
| Spain La Liga | 2020/12/29 16:00 | Sevilla v Villarreal | W | 2-0 |
| Spain La Liga | 2020/06/22 17:30 | Villarreal v Sevilla | D | 2-2 |
| Spain La Liga | 2019/12/15 17:30 | Sevilla v Villarreal | L | 1-2 |
| Spain La Liga | 2019/02/17 17:30 | Villarreal v Sevilla | L | 3-0 |
| Spain La Liga | 2018/08/26 20:15 | Sevilla v Villarreal | D | 0-0 |
| Spain La Liga | 2018/04/14 11:00 | Sevilla v Villarreal | D | 2-2 |
| Spain La Liga | 2017/11/26 17:30 | Villarreal v Sevilla | W | 2-3 |
| Spain La Liga | 2017/02/05 11:00 | Sevilla v Villarreal | D | 0-0 |
| Spain La Liga | 2016/08/28 20:15 | Villarreal v Sevilla | D | 0-0 |
| Spain La Liga | 2016/03/13 15:00 | Sevilla v Villarreal | W | 4-2 |
| Spain La Liga | 2015/10/31 17:15 | Villarreal v Sevilla | L | 2-1 |
| Spain La Liga | 2015/03/22 16:00 | Villarreal v Sevilla | W | 0-2 |
| UEFA Europa League | 2015/03/19 20:05 | Sevilla v Villarreal | W | 2-1 |
| UEFA Europa League | 2015/03/12 20:05 | Villarreal v Sevilla | W | 1-3 |
| Spain La Liga | 2014/10/26 18:00 | Sevilla v Villarreal | W | 2-1 |