[13] Puebla 2-0 Mazatlan FC [10] 2021-10-20 00:00
Stadium: Estadio Cuauhtemoc Round: 14
Referee: Jorge Antonio Perez Duran Home Manager: Nicolas Larcamon Away Manager: Benat San Jose
Head to Head
| Mexico Liga MX | 2021/04/03 01:30 | Puebla v Mazatlan FC | W | 3-1 |
| Mexico Liga MX | 2020/07/28 03:00 | Mazatlan FC v Puebla | W | 1-4 |
| Mexico Liga MX | 2016/04/03 02:30 | Mazatlan FC v Puebla | L | 2-0 |
| Mexico Liga MX | 2015/10/04 22:00 | Puebla v Mazatlan FC | L | 1-3 |
| Mexico Super Cup | 2015/07/20 22:30 | Puebla v Mazatlan FC | W | 1-0 |
| Mexico Liga MX | 2015/02/21 01:30 | Mazatlan FC v Puebla | W | 1-2 |
| Mexico Cup | 2014/09/25 00:00 | Mazatlan FC v Puebla | L | 3-0 |
| Mexico Cup | 2014/09/17 00:00 | Puebla v Mazatlan FC | W | 2-1 |
| Mexico Liga MX | 2014/08/30 22:00 | Puebla v Mazatlan FC | W | 3-2 |