[15] Toluca Women 1-0 Santos Laguna Women [4] 2021-10-09 21:00
Stadium: Estadio Nemesio Diez Round: 12
Head to Head
| Mexico Liga MX Femenil | 2021/04/19 21:00 | Toluca Women v Santos Laguna Women | W | 1-0 |
| Mexico Liga MX Femenil | 2020/11/20 01:00 | Santos Laguna Women v Toluca Women | L | 2-0 |
| Mexico Liga MX Femenil | 2019/11/12 01:00 | Toluca Women v Santos Laguna Women | W | 2-0 |