[15] Queretaro Women 4-2 Santos Laguna Women [4] 2021-11-13 23:00
Stadium: Estadio La Corregidora Round: 16
Head to Head
| Mexico Liga MX Femenil | 2021/02/09 01:00 | Santos Laguna Women v Queretaro Women | W | 1-2 |
| Mexico Liga MX Femenil | 2020/10/19 17:00 | Queretaro Women v Santos Laguna Women | W | 2-1 |
| Mexico Liga MX Femenil | 2019/08/02 21:00 | Queretaro Women v Santos Laguna Women | W | 1-0 |
| Mexico Liga MX Femenil | 2019/03/26 03:00 | Santos Laguna Women v Queretaro Women | L | 2-1 |
| Mexico Liga MX Femenil | 2019/01/28 22:00 | Queretaro Women v Santos Laguna Women | W | 4-0 |
| Mexico Liga MX Femenil | 2018/10/23 02:00 | Santos Laguna Women v Queretaro Women | D | 2-2 |
| Mexico Liga MX Femenil | 2018/08/10 21:00 | Queretaro Women v Santos Laguna Women | W | 3-1 |
| Mexico Liga MX Femenil | 2018/03/03 17:00 | Queretaro Women v Santos Laguna Women | L | 1-2 |
| Mexico Liga MX Femenil | 2018/01/16 03:00 | Santos Laguna Women v Queretaro Women | L | 3-1 |