[67] East Carolina 30-29 Memphis [59] 2021-11-13 17:00
Stadium: Liberty Bowl Memorial Stadium Round: 1
Home Manager: Ryan Silverfield Away Manager: Mike Houston
Head to Head
| NCAAF | 2018/11/03 16:00 | Memphis v East Carolina | L | 59-41 |
| NCAAF | 2017/11/25 17:00 | East Carolina v Memphis | L | 13-70 |
| NCAAF | 2012/10/13 12:00 | East Carolina v Memphis | W | 41-7 |
| NCAAF | 2011/10/15 12:00 | Memphis v East Carolina | W | 17-35 |
| NCAAF | 2010/09/11 12:00 | East Carolina v Memphis | W | 49-27 |
| NCAAF | 2009/10/27 12:00 | Memphis v East Carolina | W | 19-38 |
| NCAAF | 2008/10/18 12:00 | East Carolina v Memphis | W | 30-10 |
| NCAAF | 2007/11/03 12:00 | Memphis v East Carolina | W | 40-56 |
| NCAAF | 2006/09/16 12:00 | East Carolina v Memphis | W | 35-20 |
| NCAAF | 2005/10/22 12:00 | Memphis v East Carolina | L | 27-24 |
| NCAAF | 2004/11/20 12:00 | East Carolina v Memphis | L | 35-38 |
| NCAAF | 2003/11/01 12:00 | Memphis v East Carolina | L | 41-24 |
| NCAAF | 2001/10/20 12:00 | East Carolina v Memphis | W | 32-11 |
| NCAAF | 2000/10/07 12:00 | Memphis v East Carolina | L | 17-10 |