[125] South Florida 13-17 Central Florida [35] 2021-11-26 20:30
Stadium: Spectrum Stadium Round: 1
Home Manager: Gus Malzahn Away Manager: Jeff Scott
Head to Head
| NCAAF | 2020/11/27 20:30 | Central Florida v South Florida | L | 58-46 |
| NCAAF | 2019/11/30 01:00 | South Florida v Central Florida | L | 7-34 |
| NCAAF | 2018/11/23 21:00 | Central Florida v South Florida | L | 38-10 |
| NCAAF | 2017/11/24 20:30 | South Florida v Central Florida | L | 42-49 |
| NCAAF | 2016/11/26 17:00 | Central Florida v South Florida | W | 31-48 |
| NCAAF | 2015/11/27 00:30 | Central Florida v South Florida | W | 3-44 |
| NCAAF | 2014/11/28 17:00 | South Florida v Central Florida | L | 0-16 |
| NCAAF | 2008/09/06 12:00 | Central Florida v South Florida | W | 24-31 |
| NCAAF | 2007/10/13 12:00 | South Florida v Central Florida | W | 64-12 |
| NCAAF | 2006/09/16 12:00 | Central Florida v South Florida | W | 17-24 |
| NCAAF | 2005/09/17 12:00 | South Florida v Central Florida | W | 31-14 |