[79] Mississippi State 45-6 Vanderbilt [113] 2021-10-23 20:00
Stadium: Vanderbilt Stadium Round: 1
Home Manager: Clark Lea Away Manager: Mike Leach
Head to Head
| NCAAF | 2020/11/07 20:30 | Vanderbilt v Mississippi State | W | 17-24 |
| NCAAF | 2014/11/23 00:30 | Mississippi State v Vanderbilt | W | 51-0 |
| NCAAF | 2009/09/19 12:00 | Vanderbilt v Mississippi State | W | 3-15 |
| NCAAF | 2008/10/11 12:00 | Mississippi State v Vanderbilt | W | 17-14 |
| NCAAF | 2004/10/02 12:00 | Vanderbilt v Mississippi State | L | 31-13 |
| NCAAF | 2003/10/04 12:00 | Mississippi State v Vanderbilt | W | 30-21 |