[34] Northern Illinois 33-27 Buffalo [89] 2021-11-18 00:00
Stadium: UB Stadium Round: 1
Home Manager: Maurice Linguist Away Manager: Thomas Hammock
Head to Head
| NCAAF | 2020/11/05 00:00 | Buffalo v Northern Illinois | L | 49-30 |
| NCAAF | 2018/12/01 00:00 | Northern Illinois v Buffalo | W | 30-29 |
| NCAAF | 2017/10/14 19:30 | Northern Illinois v Buffalo | W | 14-13 |
| NCAAF | 2016/10/22 19:30 | Buffalo v Northern Illinois | W | 7-44 |
| NCAAF | 2015/11/12 01:00 | Buffalo v Northern Illinois | W | 30-41 |
| NCAAF | 2012/10/13 12:00 | Northern Illinois v Buffalo | W | 45-3 |
| NCAAF | 2011/10/22 12:00 | Buffalo v Northern Illinois | W | 30-31 |
| NCAAF | 2010/10/16 12:00 | Northern Illinois v Buffalo | W | 45-14 |
| NCAAF | 2006/09/16 12:00 | Northern Illinois v Buffalo | W | 31-13 |
| NCAAF | 2003/11/08 12:00 | Buffalo v Northern Illinois | W | 9-40 |
| NCAAF | 2000/10/28 12:00 | Northern Illinois v Buffalo | W | 73-10 |