[5] VAN Canucks 2-5 BUF Sabres [7] 2021-10-19 23:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Travis Green
Head to Head
| NHL | 2020/01/11 18:00 | VAN Canucks v BUF Sabres | W | 6-3 |
| NHL | 2019/12/07 21:00 | BUF Sabres v VAN Canucks | W | 5-6 |
| NHL | 2019/01/19 03:00 | BUF Sabres v VAN Canucks | W | 3-4 |
| NHL | 2018/11/10 18:00 | VAN Canucks v BUF Sabres | L | 3-4 |
| NHL | 2018/01/26 03:00 | BUF Sabres v VAN Canucks | L | 4-0 |
| NHL | 2017/10/20 23:00 | VAN Canucks v BUF Sabres | W | 4-2 |
| NHL | 2017/02/13 00:30 | VAN Canucks v BUF Sabres | W | 4-2 |
| NHL | 2016/10/21 02:00 | BUF Sabres v VAN Canucks | W | 1-2 |