[3] BUF Sabres 3-5 SJ Sharks [3] 2021-11-03 02:30
Stadium: SAP Center at San Jose
Home Manager: Bob Boughner Away Manager: Don Granato
Head to Head
| NHL | 2019/10/22 23:00 | SJ Sharks v BUF Sabres | W | 3-4 |
| NHL | 2019/10/20 02:30 | BUF Sabres v SJ Sharks | W | 4-3 |
| NHL | 2018/11/28 00:00 | SJ Sharks v BUF Sabres | W | 2-3 |
| NHL | 2018/10/19 02:30 | BUF Sabres v SJ Sharks | L | 1-5 |
| NHL | 2017/10/28 17:00 | SJ Sharks v BUF Sabres | L | 3-2 |
| NHL | 2017/10/13 02:30 | BUF Sabres v SJ Sharks | L | 2-3 |
| NHL | 2017/03/15 02:30 | BUF Sabres v SJ Sharks | L | 1-4 |
| NHL | 2017/02/08 00:00 | SJ Sharks v BUF Sabres | W | 4-5 |