[10] Tigres UANL 0-2 Puebla [9] 2022-01-16 01:00
Stadium: Estadio Universitario (UANL) Round: 2
Referee: Luis Enrique Santander Aguirre Home Manager: Miguel Herrera Away Manager: Nicolas Larcamon
Head to Head
| Mexico Liga MX | 2021/08/14 00:00 | Puebla v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2021/03/06 03:30 | Puebla v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2020/08/12 02:00 | Tigres UANL v Puebla | W | 2-1 |
| Mexico Liga MX | 2020/03/07 03:00 | Puebla v Tigres UANL | D | 0-0 |
| Mexico Liga MX | 2019/09/25 00:00 | Tigres UANL v Puebla | L | 0-1 |
| Mexico Liga MX | 2019/04/27 00:00 | Puebla v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2018/11/11 01:00 | Tigres UANL v Puebla | W | 6-1 |
| Mexico Cup | 2018/09/27 00:00 | Tigres UANL v Puebla | W | 4-0 |
| Mexico Liga MX | 2018/01/06 01:00 | Puebla v Tigres UANL | L | 2-1 |
| Mexico Liga MX | 2017/07/23 00:00 | Tigres UANL v Puebla | W | 5-0 |
| Mexico Liga MX | 2017/03/05 18:00 | Puebla v Tigres UANL | W | 0-2 |
| Mexico Liga MX | 2016/09/18 00:00 | Tigres UANL v Puebla | W | 2-1 |
| Mexico Liga MX | 2016/03/20 23:00 | Puebla v Tigres UANL | D | 0-0 |
| Mexico Liga MX | 2015/10/01 01:45 | Tigres UANL v Puebla | L | 0-1 |
| Mexico Liga MX | 2015/02/08 01:00 | Tigres UANL v Puebla | W | 1-0 |
| Mexico Liga MX | 2014/08/16 22:00 | Puebla v Tigres UANL | D | 1-1 |