[9] Southampton 1-2 Newcastle [14] 2022-03-10 19:30
Stadium: St. Mary's Stadium Round: 21
Referee: Kevin Friend Home Manager: Ralph Hasenhuttl Away Manager: Eddie Howe
Head to Head
| England Premier League | 2021/08/28 14:00 | Newcastle v Southampton | D | 2-2 |
| England Premier League | 2021/02/06 15:00 | Newcastle v Southampton | L | 3-2 |
| England Premier League | 2020/11/06 20:00 | Southampton v Newcastle | W | 2-0 |
| England Premier League | 2020/03/07 15:00 | Southampton v Newcastle | L | 0-1 |
| England Premier League | 2019/12/08 14:00 | Newcastle v Southampton | L | 2-1 |
| England Premier League | 2019/04/20 16:30 | Newcastle v Southampton | L | 3-1 |
| England Premier League | 2018/10/27 14:00 | Southampton v Newcastle | D | 0-0 |
| England Premier League | 2018/03/10 15:00 | Newcastle v Southampton | L | 3-0 |
| England Premier League | 2017/10/15 15:00 | Southampton v Newcastle | D | 2-2 |
| England Premier League | 2016/04/09 14:00 | Southampton v Newcastle | W | 3-1 |
| England Premier League | 2015/08/09 12:30 | Newcastle v Southampton | D | 2-2 |
| England Premier League | 2015/01/17 17:30 | Newcastle v Southampton | W | 1-2 |
| England Premier League | 2014/09/13 14:00 | Southampton v Newcastle | W | 4-0 |