[8] Guabira 1-0 Real Santa Cruz [7] 2022-04-21 22:15
Stadium: Estadio Ramon Tahuichi Aguilera Round: 10
Head to Head
| Bolivia Apertura | 2022/02/13 19:00 | Real Santa Cruz v Guabira | D | 2-2 |
| Bolivia Apertura | 2021/09/27 19:00 | Real Santa Cruz v Guabira | L | 3-0 |
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | W | 1-0 |
| Bolivia Apertura | 2020/12/29 19:00 | Real Santa Cruz v Guabira | D | 4-4 |
| Bolivia Apertura | 2020/03/15 21:15 | Guabira v Real Santa Cruz | W | 1-0 |