Eastern Illinois 35-21 Murray State 2022-09-24 21:00
Stadium: Roy Stewart Stadium Round: 1
Home Manager: Dean Hood Away Manager: Chris Wilkerson
Head to Head
| NCAAF | 2021/11/20 18:00 | Murray State v Eastern Illinois | L | 20-13 |
| NCAAF | 2021/10/02 21:00 | Eastern Illinois v Murray State | L | 6-22 |
| NCAAF | 2021/03/28 19:00 | Eastern Illinois v Murray State | L | 27-41 |
| NCAAF | 2019/10/05 18:00 | Eastern Illinois v Murray State | L | 17-24 |
| NCAAF | 2018/10/06 23:00 | Murray State v Eastern Illinois | L | 48-41 |
| NCAAF | 2017/10/14 20:00 | Murray State v Eastern Illinois | W | 24-27 |