[13] St Lucia 0-4 Birkirkara [4] 2022-09-11 18:45
Stadium: Luxol Sports Ground Round: 4
Home Manager: Pablo Cortes Away Manager: Jonathan Holland
Head to Head
| Malta Premier League | 2022/02/27 13:00 | Birkirkara v Santa Lucia FC | W | 2-3 |
| Malta Premier League | 2021/11/21 10:30 | Santa Lucia FC v Birkirkara | W | 2-0 |
| Malta Premier League | 2021/01/10 13:00 | Santa Lucia FC v Birkirkara | D | 0-0 |
| Malta Premier League | 2019/11/09 15:15 | Santa Lucia FC v Birkirkara | L | 0-2 |
| Europe Friendlies | 2018/07/26 16:09 | Birkirkara v Santa Lucia FC | L | 1-0 |
| Malta FA Trophy | 2017/12/02 13:00 | Santa Lucia FC v Birkirkara | L | 0-5 |