Stadium: Fred G. Hughes Stadium Round: 1
| NCAAF | 2022/10/29 18:00 | Missouri Western Griffons v Missouri Southern Lions | L | 31-27 |
| NCAAF | 2021/10/30 19:00 | Missouri Southern Lions v Missouri Western Griffons | L | 28-45 |
| NCAAF | 2019/10/12 21:00 | Missouri Western Griffons v Missouri Southern Lions | L | 43-34 |
| NCAAF | 2018/10/06 19:00 | Missouri Southern Lions v Missouri Western Griffons | L | 10-33 |