[3] Juan M Del Potro 6-7,6-3,7-6,6-2 John Isner [11] 2018-09-04 17:45
Stadium: Arthur Ashe Stadium Round: 27 Ground: Hardcourt outdoor
Head to Head
| French Open | 2018/06/04 14:40 | John Isner v Juan Martin Del Potro | 4-6,4-6,4-6 |
| ATP Miami | 2018/03/30 17:00 | Juan Martin Del Potro v John Isner | 1-6,6-7 |
| ATP Paris | 2017/11/03 13:00 | Juan Martin Del Potro v John Isner | 4-6,7-6,4-6 |
| ATP Montreal | 2017/08/07 22:30 | Juan Martin Del Potro v John Isner | 7-5,7-5 |
| ATP Stockholm | 2016/10/19 16:30 | John Isner v Juan Martin Del Potro | 4-6,6-7 |