Missouri State 16-23 Oklahoma State 2021-09-04 23:00
Stadium: Boone Pickens Stadium Round: 1
Home Manager: Mike Gundy Away Manager: Bobby Petrino
Head to Head
| NCAAF | 2018/08/31 00:00 | Missouri St v Oklahoma State | L | 17-58 |
| NCAAF | 2014/09/06 19:30 | Oklahoma State v Missouri St | L | 40-23 |
| NCAAF | 2008/09/13 12:00 | Oklahoma State v Missouri St | L | 57-13 |
| NCAAF | 2006/09/02 12:00 | Oklahoma State v Missouri St | L | 52-10 |
| NCAAF | 2003/09/13 12:00 | Oklahoma State v Missouri St | L | 42-3 |
Home History
| NCAAF | 2021/04/24 20:00 | Missouri St v North Dakota | L | 10-44 |
| NCAAF | 2021/04/10 19:00 | Youngstown State v Missouri St | W | 10-21 |
| NCAAF | 2021/03/27 19:00 | SO Illinois v Missouri St | W | 27-30 |
| NCAAF | 2021/03/20 21:00 | Missouri St v Northern Iowa | W | 13-6 |
| NCAAF | 2021/03/13 19:00 | Missouri St v South Dakota | W | 27-24 |
| NCAAF | 2021/03/06 20:00 | North Dakota State v Missouri St | L | 25-0 |
| NCAAF | 2021/02/27 18:00 | Missouri St v Western Illinois | W | 30-24 |
| NCAAF | 2020/10/18 00:00 | Central Arkansas v Missouri St | L | 33-24 |
Away History
| NCAAF | 2020/12/29 22:30 | Oklahoma State v Miami Florida | W | 37-34 |
| NCAAF | 2020/12/12 20:30 | Oklahoma State v Baylor | W | 42-3 |
| NCAAF | 2020/12/05 17:00 | Oklahoma State v TCU | L | 22-29 |
| NCAAF | 2020/11/28 17:00 | Texas Tech v Oklahoma State | W | 44-50 |
| NCAAF | 2020/11/22 00:30 | Oklahoma State v Oklahoma | L | 13-41 |
| NCAAF | 2020/11/07 21:00 | Oklahoma State v Kansas State | W | 20-18 |
| NCAAF | 2020/10/31 20:00 | Texas v Oklahoma State | L | 41-34 |
| NCAAF | 2020/10/24 19:30 | Iowa State v Oklahoma State | W | 21-24 |