[7] Santos Laguna 3-1 Tigres [9] 2018-08-19 23:00
Stadium: Estadio TSM Corona Round: 5
Referee: Jorge Antonio Perez Duran Home Manager: Salvador Reyes Away Manager: Ricardo Ferretti
Head to Head
| Mexico Champion of Champions | 2018/07/16 01:00 | Tigres UANL v Santos Laguna | L | 4-0 |
| Mexico Liga MX | 2018/05/06 23:00 | Santos Laguna v Tigres UANL | W | 2-0 |
| Mexico Liga MX | 2018/05/04 00:30 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2018/01/14 01:00 | Tigres UANL v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2017/07/30 23:30 | Santos Laguna v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2017/01/08 01:00 | Tigres UANL v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2016/07/17 23:00 | Santos Laguna v Tigres UANL | D | 0-0 |
| Mexico Liga MX | 2016/04/24 00:00 | Santos Laguna v Tigres UANL | W | 2-1 |
Home History
| Mexico Cup | 2018/08/16 00:00 | Club Celaya v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2018/08/12 23:00 | Chivas Guadalajara v Santos Laguna | W | 1-2 |
| Mexico Cup | 2018/08/08 00:00 | Santos Laguna v Club Celaya | D | 1-1 |
| Mexico Liga MX | 2018/08/05 23:00 | Santos Laguna v Puebla | W | 2-0 |
| Mexico Cup | 2018/08/01 02:00 | Pachuca v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2018/07/28 00:00 | Atletico Morelia v Santos Laguna | L | 3-1 |
| Mexico Liga MX | 2018/07/22 23:00 | Santos Laguna v Lobos BUAP | W | 2-1 |
| Mexico Champion of Champions | 2018/07/16 01:00 | Tigres UANL v Santos Laguna | L | 4-0 |
Away History
| Mexico Cup | 2018/08/16 02:00 | Tigres UANL v Atletico San Luis | W | 5-1 |
| Mexico Liga MX | 2018/08/12 00:00 | Tigres UANL v Toluca | L | 1-2 |
| Mexico Cup | 2018/08/09 00:00 | Tigres UANL v Cafetaleros de Tapachula FC | D | 0-0 |
| Mexico Liga MX | 2018/08/05 02:00 | Cruz Azul v Tigres UANL | L | 1-0 |
| Mexico Liga MX | 2018/07/29 23:00 | Tigres UANL v Tijuana | W | 1-0 |
| Mexico Cup | 2018/07/25 00:00 | Atletico San Luis v Tigres UANL | L | 2-1 |
| Mexico Liga MX | 2018/07/22 02:00 | Tigres UANL v Leon | W | 2-0 |
| Mexico Champion of Champions | 2018/07/16 01:00 | Tigres UANL v Santos Laguna | W | 4-0 |